MYL12A polyclonal antibody

Product Specifications

Background

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF) /Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

MYL12A; HEL-S-24; MLC-2B; MLCB; MRCL3; MRLC3; MYL2B

Swiss Prot

P19105

Reactivity

Human

Immunogen

Recombinant fusion protein of human MYL12A (NP_006462.1) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:500 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .