TGS1 polyclonal antibody
Product Specifications
Background
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m (7G caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m (2,2,7G cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs. Plays a role in transcriptional regulation.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
TGS1; NCOA6IP; PIMT; PIPMT
Swiss Prot
Q96RS0
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TGS1 (NP_079107.6) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
97kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-4040R-Biotin-TR 20 µL
IL18BP Polyclonal Antibody, Biotin Conjugated
Sign In for Pricing
View Details 
ARP55238_P050-HRP 100 µL
PPWD1 Antibody - middle region : HRP (ARP55238_P050-HRP)
Sign In for Pricing
View Details