FKBP3 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FKBP3; FKBP-25; FKBP-3; FKBP25; PPIase

Swiss Prot

Q00688

Reactivity

Human

Immunogen

Recombinant fusion protein of human FKBP3 (NP_002004.1) .

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB,1:500 - 1:2000|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .