[KO Validated] GARS polyclonal antibody

Product Specifications

Background

This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

GARS; CMT2D; DSMAV; GlyRS; HMN5; SMAD1

Swiss Prot

P41250

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human GARS (NP_002038.2) .

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:1000 - 1:4000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .