FKBP51/FKBP5 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FKBP5; AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Swiss Prot

Q13451

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human FKBP51/FKBP51/FKBP51/FKBP5 (NP_001139247.1) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:200 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .