SETD2 polyclonal antibody
Product Specifications
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
SETD2; HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; SET2; p231HBP
Swiss Prot
Q9BYW2
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SETD2 (NP_054878.5) .
Conjugation
Unconjugated
Applications
WB, IF/ICC, IP
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
288KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2075718-01 0.1 mL
HRP-Linked Polyclonal Antibody to Catenin Beta Interacting Protein 1 (CTNNbIP1)
Sign In for Pricing
View Details MBS2075718-02 0.2 mL
HRP-Linked Polyclonal Antibody to Catenin Beta Interacting Protein 1 (CTNNbIP1)
Sign In for Pricing
View Details