Cyclin A2 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CCN1; CCNA; Cyclin A2; CCNA2; cyclin-A2

Swiss Prot

P20248

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide of human Cyclin A2.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .