Prolyl hydroxylase PHD1 (EGLN2) polyclonal antibody
Product Specifications
Background
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
EGLN2; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1
Swiss Prot
Q96KS0
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human hydroxylase PHD1 (EGLN2) ) (NP_444274.1) .
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB,1:500 - 1:2000|IP,1:20 - 1:50
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
43kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
Curated Selection
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