PLC gamma 2 (PLCG2) polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PLCG2; APLAID; FCAS3; PLC-IV; PLC-gamma-2
Swiss Prot
P16885
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human PLC gamma 2 (PLC gamma 2 (PLCG2) ) (NP_002652.2) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000|IF/ICC,1:20 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
175kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6367889-01 0.2 mL
ZNF841, NT (ZNF841, Zinc finger protein 841) (AP)
Sign In for Pricing
View Details MBS6367889-02 5x 0.2 mL
ZNF841, NT (ZNF841, Zinc finger protein 841) (AP)
Sign In for Pricing
View Details