HDAC2 polyclonal antibody

Product Specifications

Background

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4) . This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

HD2; RPD3; YAF1; HDAC2

Swiss Prot

Q92769

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human HDAC2 (NP_001518.3) .

Conjugation

Unconjugated

Applications

WB, IHC, IP

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:200|IP,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .