WNK3 polyclonal antibody

Product Specifications

Background

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

WNK3; PRKWNK3

Swiss Prot

Q9BYP7

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human WNK3 (NP_065973.2) .

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB,1:200 - 1:2000|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .