PAbPC1 polyclonal antibody
Product Specifications
Background
This gene encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PABPC1; PAB1; PABP; PABP1; PABPC2; PABPL1
Swiss Prot
P11940
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PABPC1 (NP_002559.2) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
75KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
Curated Selection
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