[KO Validated] CD133 polyclonal antibody

Product Specifications

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

PROM1; AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4

Swiss Prot

O43490

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human CD133 (NP_006008.1) .

Conjugation

Unconjugated

Applications

WB, IF/ICC, IP

Dilution

WB,1:1000 - 1:3000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .