TDP-43/TARDB polyclonal antibody

Product Specifications

Background

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

ALS10; TDP-43; TARDBP; TDP43

Swiss Prot

Q13148

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human TDP-43/TARDB (NP_031401.1) .

Conjugation

Unconjugated

Applications

WB, IP, RIP

Dilution

WB,1:500 - 1:2000|IP,1:50 - 1:100|RIP,1:20 - 1:50

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .