CABLES1 polyclonal antibody

Product Specifications

Background

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127) .Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CABLES1; CABL1; CABLES; HsT2563; IK3-1

Swiss Prot

Q8TDN4

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human CABLES1 (NP_612384.1) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:1000 - 1:2000|IHC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .