IL17RB polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

IL17RB; CRL4; EVI27; IL17BR; IL17RH1

Swiss Prot

Q9NRM6

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IL17RB (NP_061195.2) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:1000 - 1:4000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .