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NRF2 polyclonal antibody

Product Specifications

Background

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

NFE2L2; HEBP1; NRF2

Swiss Prot

Q16236

Reactivity

Human, Mouse, Rat, Pig

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

110KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.

Applications Notes

Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

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