NRF2 polyclonal antibody
Product Specifications
Background
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NFE2L2; HEBP1; NRF2
Swiss Prot
Q16236
Reactivity
Human, Mouse, Rat, Pig
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
110KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.
Applications Notes
Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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