[KO Validated] HDAC1 polyclonal antibody
Product Specifications
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
GON-10; HD1; RPD3; RPD3L1; HDAC1
Swiss Prot
Q13547
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human HDAC1 (NP_004955.2) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC, IP
Dilution
WB,1:500 - 1:2000|IHC,1:100 - 1:200|IF/ICC,1:50 - 1:100|IP,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
62kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit
Available Sizes
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