CD11C (8E3) monoclonal antibody
Product Specifications
Background
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C
Swiss Prot
P20702
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids of Human CD11C
Conjugation
Unconjugated
Related Pathways
Immune checkpoint signaling in the Tumor Microenvironment, Tumor-Infiltrating Immune Cell Marker Guide
Applications
WB
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 128 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD11C (8E3) monoclonal antibody detects endogenous levels of CD 11C protein.
Applications Notes
Western blot (WB) analysis of CD11C (8E3) mAb at 1:2000 dillution Lane1:MCF-7 whole cell lysate (40μg) Lane2:HepG2 whole cell lysate (40μg)
Host or Source
Mouse
Available Sizes
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