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CD11C (8E3) monoclonal antibody

Product Specifications

Background

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C

Swiss Prot

P20702

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids of Human CD11C

Conjugation

Unconjugated

Related Pathways

Immune checkpoint signaling in the Tumor Microenvironment, Tumor-Infiltrating Immune Cell Marker Guide

Applications

WB

Dilution

WB: 1:500~1:2000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 128 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CD11C (8E3) monoclonal antibody detects endogenous levels of CD 11C protein.

Applications Notes

Western blot (WB) analysis of CD11C (8E3) mAb at 1:2000 dillution Lane1:MCF-7 whole cell lysate (40μg) Lane2:HepG2 whole cell lysate (40μg)

Host or Source

Mouse

Available Sizes

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