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SWAP70 monoclonal antibody

Product Specifications

Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4) -bisphosphate production and cell protrusion

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Switch-associated protein 70; HSPC321; SWAP-70; FLJ39540; KIAA0640

Swiss Prot

Q9UH65

Reactivity

Human, Mouse, Rat, Hamster

Immunogen

Recombinant full length Human SWAP70.

Conjugation

Unconjugated

Applications

WB IP

Dilution

WB: 1:500~1000 IP: 1:50~100

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

Predicted band size:70KDa Observed band size:70KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

This antibody detects endogenous levels of SWAP70 and does not cross-react with related proteins

Applications Notes

Western blot detection of SWAP70 in Hela, 3T3, CHO-K1 and C6 cell lysates and using SWAP70 antibody (1:500 diluted) .

Host or Source

Mouse

Available Sizes

Curated Selection

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