RanBP9 monoclonal antibody
Product Specifications
Background
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7; BPM-L; BPM90; RANBPM; RanBP7
Swiss Prot
Q96S59
Reactivity
Human
Immunogen
Recombinant full length Human RanBP9.
Conjugation
Unconjugated
Applications
WB IP ICC
Dilution
WB: 1:1000 ICC: 1:100~300 IP: 1:50~100
Purity
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
Predicted band size:78KDa Observed band size:95KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins
Applications Notes
Western blot detection of RANBP9 in Jurkat, MOLT-4&CEM cell lysates and using RANBP9 antibody (1:1000 diluted) .
Host or Source
Mouse
Available Sizes
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