MPI monoclonal antibody

Product Specifications

Background

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Phosphohexomutase; Phosphomannose isomerase; PMI; PMI1; CDG1B

Swiss Prot

P34949

Reactivity

Human, Rat

Immunogen

Recombinant full length Human MPI.

Conjugation

Unconjugated

Applications

WB ICC

Dilution

WB: 1:500~2000 ICC: 1:200~500

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .