PEG10 monoclonal antibody
Product Specifications
Background
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity) . May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Retrotransposon-derived protein PEG10; Embryonal carcinoma differentiation-regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Ty3/Gypsy-like protein; EDR; HB-1; Mar2; MEF3L; Mart2; RGAG3
Swiss Prot
Q86TG7
Reactivity
Human
Immunogen
Recombinant full length Human PEG10.
Conjugation
Unconjugated
Applications
WB IP
Dilution
WB: 1:1000 IP: 1:50~1:200
Purity
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
Predicted band size:55KDa Observed band size:55KDa/95KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
This antibody detects endogenous levels of PEG10 and does not cross-react with related proteins
Applications Notes
Western blot detection of PEG10 in Hela cell lysates using PEG10 antibody (1:1000 diluted) .
Host or Source
Mouse IgG1
Available Sizes
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