ZNF262 (H837) polyclonal antibody
Product Specifications
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF262, also known as ZMYM4, is a 1,548 amino acid protein that contains 9 MYM-type zinc fingers. Four ZNF262 isoforms are expressed due to alternative splicing events, and are found in heart, skeletal muscle, kidney and liver. Upon DNA damage, ZNF262 may be phosphorylated by ATM or ATR. The mRNA encoding ZNF262 contains a CDIR motif (cell death inhibiting RNA) which binds to HNRPD/AUF1 and HSPB1/HSP27 and can inhibit FN-γ induced apoptosis. The gene encoding ZNF262 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CDIR; Cell death inhibiting RNA; MYM; Zinc finger protein 262; Zinc finger; MYM type 4; ZMYM4; ZNF198L3
Swiss Prot
Q5VZL5
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ZNF262.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 240 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ZNF262 (H837) polyclonal antibody detects endogenous levels of ZNF262 protein.
Applications Notes
Western blot analysis of ZNF262 expression in HepG2 (A), HeLa (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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