OSGEP polyclonal antibody
Product Specifications
Background
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Probable tRNA N6-adenosine threonylcarbamoyltransferaseUniRule annotation; N6-L-threonylcarbamoyladenine synthase; t (6) A synthase; O-sialoglycoprotein endopeptidaseUniRule annotation; hOSGEP; t (6) A37 threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; OSGEP; GCPL1
Swiss Prot
Q9NPF4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human OSGEP.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 36kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
OSGEP polyclonal antibody detects endogenous levels of OSGEP protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using OSGEP antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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