OSGEP polyclonal antibody

Product Specifications

Background

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Probable tRNA N6-adenosine threonylcarbamoyltransferaseUniRule annotation; N6-L-threonylcarbamoyladenine synthase; t (6) A synthase; O-sialoglycoprotein endopeptidaseUniRule annotation; hOSGEP; t (6) A37 threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; OSGEP; GCPL1

Swiss Prot

Q9NPF4

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human OSGEP.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB: 1:500~1:2000 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .