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DAAM2 polyclonal antibody

Product Specifications

Background

DAAM2 (disheveled associated activator of morphogenesis 2), also known as KIAA0381, is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Disheveled-associated activator of morphogenesis 2; DAAM2; KIAA0381

Swiss Prot

Q86T65

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human DAAM2.

Conjugation

Unconjugated

Applications

WB, IHC, IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 123kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

DAAM2 polyclonal antibody detects endogenous levels of DAAM2 protein.

Applications Notes

Western blot analysis of extracts of various cell lines, using DAAM2 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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