DAAM2 polyclonal antibody
Product Specifications
Background
DAAM2 (disheveled associated activator of morphogenesis 2), also known as KIAA0381, is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Disheveled-associated activator of morphogenesis 2; DAAM2; KIAA0381
Swiss Prot
Q86T65
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human DAAM2.
Conjugation
Unconjugated
Applications
WB, IHC, IF
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 123kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DAAM2 polyclonal antibody detects endogenous levels of DAAM2 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using DAAM2 antibody.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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