TGM1 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Protein-glutamine gamma-glutamyltransferase K; Epidermal Tgase; Transglutaminase K; TG (K) ; TGK; TGase K; Transglutaminase-1; TGase-1; TGM1; KTG
Swiss Prot
P22735
Reactivity
Human, Rat
Immunogen
Recombinant full length Human TGM1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TGM1 polyclonal antibody detects endogenous levels of TGM1 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using TGM1 antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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