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TGM1 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Protein-glutamine gamma-glutamyltransferase K; Epidermal Tgase; Transglutaminase K; TG (K) ; TGK; TGase K; Transglutaminase-1; TGase-1; TGM1; KTG

Swiss Prot

P22735

Reactivity

Human, Rat

Immunogen

Recombinant full length Human TGM1.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:2000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 90kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TGM1 polyclonal antibody detects endogenous levels of TGM1 protein.

Applications Notes

Western blot analysis of extracts of various cell lines, using TGM1 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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