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L3MBTL3 polyclonal antibody

Product Specifications

Background

L3MBTL3 (lethal (3) malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Lethal (3) malignant brain tumor-like protein 3; H-l (3) mbt-like protein 3; L (3) mbt-like protein 3; MBT-1; L3MBTL3; KIAA1798, MBT1

Swiss Prot

Q96JM7

Reactivity

Human, Mouse

Immunogen

Recombinant full length Human L3MBTL3.

Conjugation

Unconjugated

Applications

WB IF IP

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 110 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

L3MBTL3 polyclonal antibody detects endogenous levels of L3MBTL3 protein.

Applications Notes

Western blot analysis of extracts of various cell lines, using L3MBTL3 antibody at 1:1000 dilution.

Host or Source

Rabbit

Available Sizes

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