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SETBP1 polyclonal antibody

Product Specifications

Background

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

SET-binding protein; SEB; SETBP1; KIAA0437

Swiss Prot

Q9Y6X0

Reactivity

Human, Rat

Immunogen

Recombinant full length Human SETBP1.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB: 1:500~1:2000 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 175kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

SETBP1 polyclonal antibody detects endogenous levels of SETBP1 protein.

Applications Notes

Western blot analysis of extracts of various cell lines, using SETBP1 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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