FCN1 polyclonal antibody

M-ficolin, also known as ficolin-A, ficolin-1, ficolin-α, FCN1, FCNM or collagen/fibrinogen domain containing protein 1, is a 326 amino acid member of the ficolin lectin family. Characteristic of ficolin family proteins, M-ficolin contains a short N-terminus, one collagen-like domain and one fibrinogen-like domain at its C-terminus. M-ficolin is a secreted innate immunity pattern recognition molecule predominantly expressed in peripheral blood leukocytes. It is believed to function as a plasma protein and is known to interact with elastin, carbohydrates and corticosteroids. M-ficolin exists as a homopolymer through intermolecular disulfide bonding and is involved in activating lectin activity via association with MASPs and specific carbohydrate ligands.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .