MDH2 polyclonal antibody

Product Specifications

Background

MDH2 (malate dehydrogenase, NAD mitochondrial), also known as MDH, MOR1 or M-MDH, is a 338 amino acid that belongs to the LDH/MDH superfamily. MDH2 localizes to the mitochondria and may play a critical role in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. MDH2 utilizes the NAD/NADH cofactor system in the citric acid cycle to catalyze the reversible oxidation of malate to oxaloacetate. Oxaloacetate is involved in many important metabolic pathways including amino acid synthesis, gluconeogenesis and facilitation of the exchange of metabolites between cytoplasm and subcellular organelles.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Malate dehydrogenase; mitochondrial; MDH2

Swiss Prot

P40926

Reactivity

Human, Mouse

Immunogen

Recombinant full length Human MDH2.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:2000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .