IFIT3 polyclonal antibody
Product Specifications
Background
IFIT3 (interferon-induced protein with tetratricopeptide repeats 3), also known as IRG2, IFI60, IFIT4, ISG60 or RIG-G, is a 490 amino acid protein that contains eight TPR repeats and may play a role in cell cycle regulation and cellular proliferation. The gene encoding IFIT3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CIG-49; cig41; GARG-49; IFI60; IFIT4; IRG2; ISG60; P60; RIG-G
Swiss Prot
O14879
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of mouse IFIT3
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB 1:500 - 1:1000 IHC 1:100 - 1:200 IF 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IFIT3 polyclonal antibody detects endogenous levels of IFIT3 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using IFIT3 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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