RNF220 polyclonal antibody
Product Specifications
Background
E3 ubiquitin-protein ligase RNF220, E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity) . Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
C1orf164
Swiss Prot
Q5VTB9
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human RNF220
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
75kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNF220 polyclonal antibody detects endogenous levels of RNF220 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using RNF220 antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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