AFF4 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31; q31q23) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
AF5Q31; CHOPS; MCEF
Swiss Prot
Q9UHB7
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human AFF4
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
150kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
AFF4 polyclonal antibody detects endogenous levels of AFF4 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using AFF4 antibody at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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