LINGO1 polyclonal antibody
Product Specifications
Background
Functional component of the Nogo receptor signaling complex in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
LERN1; LRRN6A; UNQ201
Swiss Prot
Q96FE5
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human LINGO1
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
70kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LINGO1 polyclonal antibody detects endogenous levels of LINGO1 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using LINGO1 antibody at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
Curated Selection
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