TRPC1 polyclonal antibody
Product Specifications
Background
Human TRPC1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain, and adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The activation of store-mediated Ca2+ entry in human cells occurs through the association between inositol 1,4,5-trisphosphate receptors and TRPC1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1; TRP1
Swiss Prot
P48995
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human TRPC1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 91 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TRPC1 polyclonal antibody detects endogenous levels of TRPC1 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using TRPC1 antibody at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
Curated Selection
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