SSNA1 polyclonal antibody

SSNA1 (Sjoegren syndrome nuclear autoantigen 1), also known as N14 or NA-14 (nuclear autoantigen of 14 kDa), is a 119 amino acid nuclear and cytoplasmic protein that is widely expressed and belongs to the SSNA1 family. While most highly expressed in testis, SSNA1 is found at lower levels in peripheral blood leukocytes, spleen, colon, thymus, ovary, prostate and small intestine, and is thought to be associated with microtubule structures. SSNA1 contains an N-terminal dimeric coiled-coil domain, a C-terminal basic domain and may target spastin activity at the centrosome. The gene encoding SSNA1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .