CBLC polyclonal antibody
Product Specifications
Background
This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CBL-3; RNF57; CBL-SL
Swiss Prot
Q9ULV8
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human CBLC.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CBLC polyclonal antibody detects endogenous levels of CBLC protein.
Applications Notes
Western blot analysis of extracts of various cells, using CBLC antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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