PSTPIP1 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S
Swiss Prot
O43586
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PSTPIP1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 48 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PSTPIP1 polyclonal antibody detects endogenous levels of PSTPIP1 protein.
Applications Notes
Western blot analysis of extracts of various cells, using PSTPIP1 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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