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PSTPIP1 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S

Swiss Prot

O43586

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSTPIP1.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 48 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PSTPIP1 polyclonal antibody detects endogenous levels of PSTPIP1 protein.

Applications Notes

Western blot analysis of extracts of various cells, using PSTPIP1 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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