SNRNP70 polyclonal antibody
Product Specifications
Background
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70; RNPU1Z; RPU1; SNRP70; U1AP1
Swiss Prot
P08621
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SNRNP70.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500 - 1:1000 IHC 1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SNRNP70 polyclonal antibody detects endogenous levels of SNRNP70 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using SNRNP70 antibody.
Host or Source
Rabbit
Available Sizes
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