TMEM173 polyclonal antibody
Product Specifications
Background
TMEM173, also named as ERIS, MITA, STING and MPYS, is a facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta) . TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. There’re monomer (40 kDa) and dimer (80 kDa) form of TMEM173 in western blot test.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Stimulator of interferon genes protein; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173; TMEM173; ERIS; MITA; STING
Swiss Prot
Q86WV6
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human TMEM173.
Conjugation
Unconjugated
Related Pathways
STING Signaling
Applications
WB IHC IP
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TMEM173 polyclonal antibody detects endogenous levels of TMEM173 protein.
Applications Notes
Western blot analysis of extract of various cells, using TMEM173 antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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