Cathepsin L2 (L114) polyclonal antibody

Product Specifications

Background

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cathepsin L2; Cathepsin U; Cathepsin V; CTSV; CATL2; CTSL2; CTSU; UNQ268; PRO305

Swiss Prot

O60911

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 91-140 of Human Cathepsin L2.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 37 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Cathepsin L2 (L114) polyclonal antibody detects endogenous levels of Cathepsin L2 protein.

Applications Notes

Western blot (WB) analysis of Cathepsin L2 (L114) pAb at 1:1000 dilution Lane1:The Testis tissue lysate of Mouse (40ug) Lane2:The Testis tissue lysate of Rat (40ug) Lane3:L02 whole cell lysate (20ug) Lane4:A375 whole cell lysate (20ug)