Ghrelin polyclonal antibody
Product Specifications
Background
Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary. Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R) . Ghrelin and GHRH are involved in the regulation of GH release from the pituitary. GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary. The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue. GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. The gene encoding ghrelin maps to human chromosome 3p26-p25.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin; Ghrelin/obestatin prepropeptide; ghrl; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; Growth hormone-releasing peptide; M46 protein; Motilin related peptide; Motilin-related peptide; MTLRP; Obestatin; Protein M46
Swiss Prot
Q9UBU3
Reactivity
Human, Rat
Immunogen
Recombinant full length Human Ghrelin.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 13 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Ghrelin polyclonal antibody detects endogenous levels of Ghrelin protein.
Applications Notes
Western blot analysis of extracts of HeLa cell lines, using Ghrelin antibody.
Host or Source
Rabbit
Available Sizes
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