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Ghrelin polyclonal antibody

Product Specifications

Background

Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary. Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R) . Ghrelin and GHRH are involved in the regulation of GH release from the pituitary. GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary. The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue. GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. The gene encoding ghrelin maps to human chromosome 3p26-p25.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin; Ghrelin/obestatin prepropeptide; ghrl; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; Growth hormone-releasing peptide; M46 protein; Motilin related peptide; Motilin-related peptide; MTLRP; Obestatin; Protein M46

Swiss Prot

Q9UBU3

Reactivity

Human, Rat

Immunogen

Recombinant full length Human Ghrelin.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:2000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 13 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Ghrelin polyclonal antibody detects endogenous levels of Ghrelin protein.

Applications Notes

Western blot analysis of extracts of HeLa cell lines, using Ghrelin antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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