Catenin-δ1 polyclonal antibody
Product Specifications
Background
The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Catenin δ1; Catenin delta-1; Cadherin-associated Src substrate; Short name=CAS; p120 catenin; p120 (ctn) ; p120 (cas) ; CTNND1; KIAA0384
Swiss Prot
O60716
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human Catenin-δ1.
Conjugation
Unconjugated
Related Pathways
Contribution of ECM and Cytoskeletal Factors to EMT
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 108 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Catenin-δ1 polyclonal antibody detects endogenous levels of Catenin-δ1 protein.
Applications Notes
Western blot analysis of Catenin-δ1 polyclonal antibody
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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