What is the catalog number for ATM (phospho-S1981) polyclonal antibody?

The catalog number for ATM (phospho-S1981) polyclonal antibody is BS64019.

What sizes are available for ATM (phospho-S1981) polyclonal antibody?

ATM (phospho-S1981) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does ATM (phospho-S1981) polyclonal antibody come in?

ATM (phospho-S1981) polyclonal antibody is available in 2 different pack sizes.

Is ATM (phospho-S1981) polyclonal antibody in stock?

ATM (phospho-S1981) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

ATM (phospho-S1981) polyclonal antibody

Product Specifications

Background

The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM

Swiss Prot

Q13315

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ATM around the phosphorylation site of ser1981.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylation

Molecular Weight

~ 370 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

P-ATM (S1981) polyclonal antibody detects endogenous levels of ATM protein only when phosphorylated at ser1981.

Applications Notes

Western blot (WB) analysis of p-ATM (S1981) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate treated with colchicine (0.2ng/ml,24h) Lane2:Raw264.7 whole cell lysate treated with colchicine (0.2ng/ml,24h) Lane3:H9C2 whole cell lysate treated with colchicine (0.2ng/ml,24h)