ADSS polyclonal antibody

Cellular signal transduction pathways are initiated by the binding of external signals, such as steroids, charged-small molecules or proteins, to their respective receptors. These signaling pathways are important in eliciting a cellular response to external stimuli. Proteins involved in signaling pathways may have several different regulatory and/or enzymatic functions, including recruitment, activation, phosphorylation, maintenance and transport. Mutations in these pathways may be implicated in a variety of diseases, suggesting that these intermediary proteins may be potential therapeutic targets. Adenylosuccinate synthetase 2 (AdSS2 or AMPSase 2) is important in the AMP biosynthesis pathway (purine nucleotide biosynthesis) . It is a cytoplasmic protein that belongs to the adenylosuccinate synthetase family of proteins. AdSS2 can form homodimers.

Adenylosuccinate synthetase isozyme 2; AMPSase 2; AdSS 2; Adenylosuccinate synthetase, acidic isozyme; Adenylosuccinate synthetase, liver isozyme; L-type adenylosuccinate synthetase; IMP--aspartate ligase 2; ADSS; ADSS2

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .