BLZF1 polyclonal antibody

Product Specifications

Background

Golgin 45, also known as JEM-1 or Basic Leucine Zipper Nuclear Factor 1, is a 400 amino acid protein that localizes to the lumen of the golgi apparatus. The primary function of golgin 45 is to maintain normal golgi structure and to facilitate protein transport from the endoplasmic reticulum to the cell surface. The latter process is regulated primarily through the interaction of golgin 45 and GRASP55, which, together, form a Rab 2 effector complex.Excluding formation of a Rab 2 complex, golgin 45 does not interact with any other golgi Rab proteins. Golgin 45 is expressed as two isoforms, one of which localizes to the nucleus and is thought to function as a transcription factor.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Golgin-45; Basic leucine zipper nuclear factor 1; JEM-1; p45 basic leucine-zipper nuclear factor; BLZF1; JEM1

Swiss Prot

Q9H2G9

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human BLZF1.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .